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Review

Buprenorphine for Opioid Use Disorder: A Review of Comparative Clinical Effectiveness, Safety, Cost-Effectiveness, and Guidelines [Internet]

Ottawa (ON): Canadian Agency for Drugs and Technologies in Health; 2019 Apr 24.
Review

Buprenorphine for Opioid Use Disorder: A Review of Comparative Clinical Effectiveness, Safety, Cost-Effectiveness, and Guidelines [Internet]

Dave K. Marchand et al.

Excerpt

CADTH has previously reviewed the evidence for the use of buprenorphine formulations for the treatment of opioid use disorders (OUDs). One report was limited to pregnant populations, another was a qualitative review of patient preferences and perspectives, and the third was a summary of abstracts based on evidence available in 2017. The objective of the current report is to evaluate the comparative clinical effectiveness, safety, cost-effectiveness and evidencebased guidelines regarding various buprenorphine or combination product of buprenorphine with naloxone (BUP-NAL) formulations for the treatment of OUD.

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Funding: CADTH receives funding from Canada’s federal, provincial, and territorial governments, with the exception of Quebec.