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Review
. 2019 Jul 10;17(1):82.
doi: 10.1186/s12951-019-0514-y.

Nano-drug delivery systems in wound treatment and skin regeneration

Wei Wang  1   2 , Kong-Jun Lu  2 , Chao-Heng Yu  3 , Qiao-Ling Huang  4 , Yong-Zhong Du  5
Affiliations
Review

Nano-drug delivery systems in wound treatment and skin regeneration

Wei Wang et al. J Nanobiotechnology. .

Abstract

Skin damages are defined as one of most common lesions people suffer from, some of wounds are notoriously difficult to eradicate such as chronic wounds and deep burns. Existing wound therapies have been proved to be inadequate and far from satisfactory. The cutting-edge nanotechnology offers an unprecedented opportunity to revolutionize and invent new therapies or boost the effectiveness of current medical treatments. In particular, the nano-drug delivery systems anchor bioactive molecules to applied area, sustain the drug release and explicitly enhance the therapeutic efficacies of drugs, thus making a fine figure in field relevant to skin regeneration. This review summarized and discussed the current nano-drug delivery systems holding pivotal potential for wound healing and skin regeneration, with a special emphasis on liposomes, polymeric nanoparticles, inorganic nanoparticles, lipid nanoparticles, nanofibrous structures and nanohydrogel.

Keywords: Nano-drug delivery system; Skin regeneration; Wound treatment.

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Conflict of interest statement

The authors declare that they have no competing interests.

Figures

Fig. 1
Fig. 1
Illustration of wound healing process
Fig. 2
Fig. 2
Nano-drug delivery systems in skin regeneration and wound treatment
See this image and copyright information in PMC

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