Treatment of severe periodontitis may improve clinical disease activity in otherwise treatment-refractory rheumatoid arthritis patients

Affiliations

¹ Department of Rheumatology, Immunology and Allergology, Inselpital - University Hospital Bern, Bern, Switzerland.
² School of Dental Medicine, Department of Periodontology, University of Bern, Bern, Switzerland.
³ Department of Microbiology, Faculty of Biochemistry, Biophysics and Biotechnology, Jagiellonian University, Krakow, Poland.
⁴ Department of Oral Immunology and Infectious Diseases, University of Louisville School of Dentistry, Louisville, KY, USA.
⁵ Kennedy Institute of Rheumatology, University of Oxford, Oxford, UK.

Burkhard Möller et al. Rheumatology (Oxford). 2020.

. 2020 Jan 1;59(1):243-245.

doi: 10.1093/rheumatology/kez287.

¹ Department of Rheumatology, Immunology and Allergology, Inselpital - University Hospital Bern, Bern, Switzerland.
² School of Dental Medicine, Department of Periodontology, University of Bern, Bern, Switzerland.
³ Department of Microbiology, Faculty of Biochemistry, Biophysics and Biotechnology, Jagiellonian University, Krakow, Poland.
⁴ Department of Oral Immunology and Infectious Diseases, University of Louisville School of Dentistry, Louisville, KY, USA.
⁵ Kennedy Institute of Rheumatology, University of Oxford, Oxford, UK.

No abstract available

References

1. Engström M, Eriksson K, Lee L et al. Increased citrullination and expression of peptidylarginine deiminases independently of P. gingivalis and A. actinomycetemcomitans in gingival tissue of patients with periodontitis. J Transl Med 2018;16:214. - PMC - PubMed
1. Schwenzer A, Quirke AM, Marzeda AM et al. Association of distinct fine specificities of anti-citrullinated peptide antibodies with elevated immune responses to Prevotella intermedia in a subgroup of patients with rheumatoid arthritis and periodontitis. Arthritis Rheumatol 2017;69:2303–13. - PMC - PubMed
1. Salemi S, Biondo MI, Fiorentino C et al. Could early rheumatoid arthritis resolve after periodontitis treatment only?: case report and review of the literature. Medicine (Baltimore) 2014;93:e195. - PMC - PubMed
1. Monsarrat P, de Grado GF, Constantin A et al. The effect of periodontal treatment on patients with rheumatoid arthritis: the ESPERA randomised controlled trial. Jt Bone Spine 2019; Advance Access published 26 February 2019, doi: 10.1016/j.jbspin.2019.02.006. - PubMed
1. Keestra JAJ, Grosjean I, Coucke W, Quirynen M, Teughels W. Non-surgical periodontal therapy with systemic antibiotics in patients with untreated chronic periodontitis: a systematic review and meta-analysis. J Periodontal Res 2015;50:294–314. - PubMed