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. 2019 Oct;25(7):1744-1750.
doi: 10.1111/odi.13154. Epub 2019 Aug 1.

Validating the Xerostomia Inventory in a radiation-induced xerostomia population in German language

Ralph Hohenberger  1 , Ingo Baumann  1 , Peter K Plinkert  1 , Regina Brinster  2 , Johannes Krisam  2 , Annette Affolter  1 , Matti Hein  3 , Paul Flechsig  4 , Hendrik Rathke  4 , Dare Oladokun  5 , Burkard M Lippert  3 , Olcay Cem Bulut  1   3
Affiliations

Validating the Xerostomia Inventory in a radiation-induced xerostomia population in German language

Ralph Hohenberger et al. Oral Dis. 2019 Oct.

Abstract

Objectives: Though xerostomia is a frequent oral symptom, there is no validated disease-specific questionnaire in German. The purpose of this study was to translate and validate versions of the Xerostomia Inventory and the Summated Xerostomia Inventory in a German-speaking population.

Participants and methods: Thirty-nine patients including 18 patients suffering from radiation-induced xerostomia enrolled in this study. Both questionnaires were translated into German language according to international accepted guidelines. For validation, we evaluated reliability, validity, and responsiveness using the COSMIN manual for cross-cultural adaptation.

Results: Cronbach's α was 0.92 for XI and 0.91 for SXI, showing both high internal consistency. Patients suffering from xerostomia showed significantly higher average scores demonstrating its discriminant validity. Confirmatory factor analysis showed excellent "goodness-of-fit" values for SXI and good to moderate values for XI, confirming the assumed factor structures. The Xerostomia Inventory and its summated version both showed excellent test-retest reliability in the non-xerostomia group (ICC = 0.85 and 0.84).

Conclusions: The XI and SXI in their cross-cultural adapted versions are the first validated self-report assessments for xerostomia in German language. They are characterized by practical design and can be easily interpreted by the treating physician.

Keywords: quality of life; sialendoscopy; summated xerostomia inventory; xerostomia; xerostomia inventory.

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