Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Comment
. 2019 Jul 12;365(6449):119-120.
doi: 10.1126/science.aax6331.

Boosting engineered T cells

Affiliations
Comment

Boosting engineered T cells

Nathan Singh et al. Science. .
No abstract available

PubMed Disclaimer

Figures

Vaccination strategy to boost antitumor efficacy
Vaccination strategy to boost antitumor efficacy
In mice, the amph-ligand vaccine results in stimulation and proliferation of engineered chimeric antigen receptor (CAR)–T cells in lymph nodes. These then migrate to solid tumors, where they have improved proliferation and enhanced efficacy.

Comment on

References

    1. Schuster SJ et al. , N. Engl. J. Med. 380, 45 (2019). - PubMed
    1. Maude SL et al. , N. Engl. J. Med. 378, 439 (2018). - PMC - PubMed
    1. Park JH et al. , N. Engl. J. Med. 378, 449 (2018). - PMC - PubMed
    1. Ma L et al. , Science 365, 162 (2019). - PMC - PubMed
    1. Philip M et al. , Nature 545, 452 (2017). - PMC - PubMed