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. 2019 Jul 12;365(6449):122-123.
doi: 10.1126/science.aaw2368.

Stromal directives can control cancer

Thea D Tlsty  1 , Philippe Gascard  2
Affiliations

Stromal directives can control cancer

Thea D Tlsty et al. Science. .
No abstract available

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Chronic inflammation–associated cancer pathogenesis
The pathogenic evolution of chronic inflammation–associated cancers (CIACs) involves metaplasia, dysplasia, and then cancer. During this process, multiple changes take place within the tissue microenvironment, including changes in stromal cells (immune cells, endothelial cells, and fibroblasts) and the extracellular matrix (ECM).
See this image and copyright information in PMC

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