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. 1988 Feb;32(2):255-6.
doi: 10.1128/AAC.32.2.255.

In vitro evaluation of josamycin, spiramycin, and erythromycin against Rickettsia rickettsii and R. conorii

D Raoult  1 , P Roussellier, J Tamalet
Affiliations

In vitro evaluation of josamycin, spiramycin, and erythromycin against Rickettsia rickettsii and R. conorii

D Raoult et al. Antimicrob Agents Chemother. 1988 Feb.

Abstract

The antimicrobial activities of josamycin, erythromycin, and spiramycin against Rickettsia conorii and R. rickettsii were evaluated in two tests: a dye-uptake assay and a plaque assay. The MIC of josamycin was 1 microgram/ml for both species; the MICs of erythromycin and spiramycin were 4 to 8 and 16 to 32 micrograms/ml, respectively, for both species. Only josamycin may be of clinical use in treating spotted fever rickettsiosis. It may be useful in treating pregnant women and young children.

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References

    1. J Infect Dis. 1974 Dec;130(6):564-74 - PubMed
    1. J Infect Dis. 1984 Oct;150(4):480-8 - PubMed
    1. Pathol Biol (Paris). 1985 May;33(5):295-6 - PubMed
    1. Kansenshogaku Zasshi. 1985 May;59(5):486-8 - PubMed
    1. J Antimicrob Chemother. 1987 Mar;19(3):303-5 - PubMed

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