Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2019 Jul 11;12(7):e229829.
doi: 10.1136/bcr-2019-229829.

Brugada pattern: a comprehensive review on the demographic and clinical spectrum

Hassan Abbas  1 , Sohaib Roomi  1 , Waqas Ullah  1 , Asrar Ahmad  1 , Ganesh Gajanan  1
Affiliations
Review

Brugada pattern: a comprehensive review on the demographic and clinical spectrum

Hassan Abbas et al. BMJ Case Rep. .

Abstract

A prominent coved or saddle-shaped ST-segment elevation followed by T wave changes in V1-V3 and in the absence of other identifiable cause is termed as Brugada pattern. This pattern in the presence of documented ventricular arrhythmias or its symptoms (syncope, seizure) or significant family for sudden cardiac death or abovementioned ECG changes is called Brugada syndrome. Here we present a comprehensive literature review on the precipitation factors of Brugada syndrome/pattern by various stimuli, its presentation, associations, management and outcomes. We are also presenting a unique case of Brugada pattern where the patient's Brugada pattern was unmasked at an extreme old age by infection.

Keywords: arrhythmias; cardiovascular medicine.

PubMed Disclaimer

Conflict of interest statement

Competing interests: None declared.

Figures

Figure 1
Figure 1
ECG showing normal sinus rhythm and no signs of ischaemia.
Figure 2
Figure 2
ECG showing coved ST-segment elevation with T wave inversion in V1 and V2 consistent with type 1 Brugada pattern.
Figure 3
Figure 3
Left coronary artery on angiography is clean with no obstruction.
Figure 4
Figure 4
Right coronary artery on angiography does not show any obstruction.
Figure 5
Figure 5
ECG shows resolution of the ST elevation.
See this image and copyright information in PMC

References

    1. Gehi AK, Duong TD, Metz LD, et al. . Risk stratification of individuals with the Brugada electrocardiogram: a meta-analysis. J Cardiovasc Electrophysiol 2006;17:577–83. 10.1111/j.1540-8167.2006.00455.x - DOI - PubMed
    1. Miyasaka Y, Tsuji H, Yamada K, et al. . Prevalence and mortality of the Brugada-type electrocardiogram in one city in Japan. J Am Coll Cardiol 2001;38:771–4. 10.1016/S0735-1097(01)01419-X - DOI - PubMed
    1. Patel SS, Anees S, Anees SS, et al. . Prevalence of a Brugada pattern electrocardiogram in an urban population in the United States. Pacing Clin Electrophysiol 2009;32:704–8. 10.1111/j.1540-8159.2009.02354.x - DOI - PubMed
    1. Hanna EB, Glancy DL. ST-segment elevation: Differential diagnosis, caveats. Cleve Clin J Med 2015;82:373–84. 10.3949/ccjm.82a.14026 - DOI - PubMed
    1. Antzelevitch C, Brugada P, Borggrefe M, et al. . Brugada syndrome: report of the second consensus conference: endorsed by the Heart Rhythm Society and the European Heart Rhythm Association. Circulation 2005;111:659–70. 10.1161/01.CIR.0000152479.54298.51 - DOI - PubMed

Substances