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Review
. 2019 Sep;7(3):270-281.
doi: 10.1016/j.esxm.2019.06.003. Epub 2019 Jul 10.

Effect of Bariatric Surgery on Male Sexual Function: A Meta-Analysis and Systematic Review

Jiangnan Xu  1 , Qian Wu  2 , Yuhui Zhang  3 , Changsong Pei  4
Affiliations
Review

Effect of Bariatric Surgery on Male Sexual Function: A Meta-Analysis and Systematic Review

Jiangnan Xu et al. Sex Med. 2019 Sep.

Abstract

Introduction: Obesity is a worldwide public health issue with serious psychological and social impacts. Erectile dysfunction is also a common clinical condition, and obesity is one of its main risk factors.

Objective: The objective of this study was to systematically evaluate the effect of bariatric surgery on male sexual function.

Methods: A systematical research was carried out in Medline via PubMed, EMBASE, Cochrane Library, and Web of Science up to March 16, 2019, to identify published articles related to bariatric surgery and male sexual function in men. Two reviewers screened literature, extracted data, and assessed the quality of included studies. I2 index was applied to estimate the heterogeneity. All analyses were done using RevMan5.3 and Stata14.

Results: A total of 12 studies involving 420 participants were included. Analysis showed that bariatric surgery significantly reduced body mass index in morbidly obese patients (mean difference [MD] = -13.73; 95% CI -17.23 to -10.22; P < .00001). From 10 studies that reported the International Index of Erectile Function (IIEF) score, bariatric surgery led to a significant increase in IIEF-total score (MD = 8.2; 95% CI = 5.52-10.88; P < .00001), and erectile function score (MD = 3.76; 95% CI = 2.34-5.19; P < .00001), sexual desire (MD = 0.93; 95% CI = 0.55-1.32; P < .00001), sexual intercourse satisfaction (MD = 1.73; 95% CI = 0.43-3.03; P < .01), and total satisfaction (MD = 1.28; 95% CI = 0.56-2.00; P = .0005) were also significantly improved. However, bariatric surgery did not affect orgasm function (MD = 0.26; 95% CI = -0.15 to 0.68; P = .21). Three studies that reported the IIEF-5 score also showed a significant improvement of erectile function (MD = 5.45; 95% CI = 3.38-7.52; P < .00001).

Conclusions: Bariatric surgery could improve the erectile function, sexual desire, sexual intercourse satisfaction, and total satisfaction in morbidly obese men. Due to limited data on body mass index and hormone levels, our meta-analysis had some limitations. More clinical studies are needed to further explore the relationship between bariatric surgery and male sexual function. Xu J, Wu Q, Zhang Y, et al. Effect of Bariatric Surgery on Male Sexual Function: A Meta-Analysis and Systematic Review. Sex Med 2019;7:270-281.

Keywords: Bariatric Surgery; Erectile Function; Meta-Analysis; Obesity; Sexual Function; Systematic Review.

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Figures

Figure 1
Figure 1
Literature search and selection process.
Figure 2.1
Figure 2.1
Forest plot-comparison of preoperative and postoperative International Index of Erectile Function-Total Score.
Figure 2.2
Figure 2.2
Forest plot-comparison of preoperative and postoperative International Index of Erectile Function score.
Figure 2.3
Figure 2.3
Forest plot-comparison of preoperative and postoperative International Index of Erectile Function-Desire.
Figure 2.4
Figure 2.4
Forest plot-comparison of preoperative and postoperative International Index of Erectile Function-Orgasm Function.
Figure 2.5
Figure 2.5
Forest plot-comparison of preoperative and postoperative International Index of Erectile Function-Intercourse Satisfaction.
Figure 2.6
Figure 2.6
Forest plot-comparison of preoperative and postoperative International Index of Erectile Function-Total Satisfaction.
Figure 2.7
Figure 2.7
Forest plot-comparison of preoperative and postoperative Five-Item International Index of Erectile Function.
Figure 3.1
Figure 3.1
Forest plot-comparison of preoperative and postoperative body mass index.
Figure 3.2
Figure 3.2
Forest plot-comparison of preoperative and postoperative Total Testosterone.
Figure 3.3
Figure 3.3
Forest plot-comparison of preoperative and postoperative Free Testosterone.
Figure 4
Figure 4
Forest plots for sensitivity analysis. BMI = body mass index; IIEF, International Index of Erectile Function.
Figure 5
Figure 5
Publication bias - Egger graphs. BMI = body mass index; IIEF, International Index of Erectile Function.
See this image and copyright information in PMC

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References

    1. Ng M., Fleming T., Robinson M. Global, regional, and national prevalence of overweight and obesity in children and adults during 1980-2013: A systematic analysis for the Global Burden of Disease Study 2013. Lancet. 2014;384:766–781. - PMC - PubMed
    1. NCD Risk Factor Collaboration (NCD-RisC) Worldwide trends in body-mass index, underweight, overweight, and obesity from 1975 to 2016: A pooled analysis of 2416 population-based measurement studies in 128.9 million children, adolescents, and adults. Lancet. 2017;390:2627–2642. - PMC - PubMed
    1. Adams K.F., Schatzkin A., Harris T.B. Overweight, obesity, and mortality in a large prospective cohort of persons 50 to 71 years old. N Engl J Med. 2006;355:763–778. - PubMed
    1. LeBlanc E.S., Patnode C.D., Webber E.M. Behavioral and pharmacotherapy weight loss interventions to prevent obesity-related morbidity and mortality in adults: Updated Evidence Report and Systematic Review for the US Preventive Services Task Force. JAMA. 2018;320:1172–1191. - PubMed
    1. Pastuszak A.W., Badhiwala N., Lipshultz L.I. Depression is correlated with the psychological and physical aspects of sexual dysfunction in men. Int J Impot Res. 2013;25:194–199. - PubMed