Inflammasomes Assemble: Cytoplasmic Guardians or Fallen Heroes?
- PMID: 31305304
- PMCID: PMC7043370
- DOI: 10.1097/CCM.0000000000003872
Inflammasomes Assemble: Cytoplasmic Guardians or Fallen Heroes?
Comment on
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Association of Elevated Plasma Interleukin-18 Level With Increased Mortality in a Clinical Trial of Statin Treatment for Acute Respiratory Distress Syndrome.Crit Care Med. 2019 Aug;47(8):1089-1096. doi: 10.1097/CCM.0000000000003816. Crit Care Med. 2019. PMID: 31206358 Free PMC article. Clinical Trial.
References
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- Martinon F, Burns K, Tschopp J. The inflammasome: a molecular platform triggering activation of inflammatory caspases and processing of proIL-beta. Mol Cell 2002; 10: 417–426. - PubMed
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- Strowig T, Henao-Mejia J, Elinav E, Flavell R. Inflammasomes in health and disease. Nature 2012; 481: 278–286. - PubMed
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- Howrylak JA, Nakahira K. Inflammasomes: Key Mediators of Lung Immunity. Annu Rev Physiol 2017; 79: 471–494. - PubMed
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