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Review
. 2019 Nov;95(3):114856.
doi: 10.1016/j.diagmicrobio.2019.06.008. Epub 2019 Jun 24.

Fosfomycin for treatment of multidrug-resistant pathogens causing urinary tract infection: A real-world perspective and review of the literature

Ahmed Babiker  1 , Lloyd Clarke  1 , Yohei Doi  1 , Ryan K Shields  2
Affiliations
Review

Fosfomycin for treatment of multidrug-resistant pathogens causing urinary tract infection: A real-world perspective and review of the literature

Ahmed Babiker et al. Diagn Microbiol Infect Dis. 2019 Nov.

Abstract

Among 47 patients with urinary tract infections (UTIs) due to multidrug-resistant (MDR) bacteria, treatment with fosfomycin resulted in clinical cure rates of 87% and 94% at 48 hours and 14 days, respectively. Response rates did not vary across pathogens. Our retrospective, observational findings support fosfomycin treatment against MDR pathogens causing UTIs.

Keywords: CRE; ESBL; Fosfomycin; UTI; VRE.

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