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Case Reports
. 2019;58(14):2025-2028.
doi: 10.2169/internalmedicine.2293-18. Epub 2019 Jul 15.

Familial Mediterranean Fever with Small Bowel Stenosis

Keita Kasamaki  1 , Chika Kusano  1 , Hisatomo Ikehara  1 , Sho Suzuki  1 , Mitsuru Esaki  1 , Akira Irie  1 , Kaori Hayashi  1 , Hiroaki Okuno  1 , Mitsuhiko Moriyama  1 , Takuji Gotoda  1
Affiliations
Case Reports

Familial Mediterranean Fever with Small Bowel Stenosis

Keita Kasamaki et al. Intern Med. 2019.

Abstract

A 37-year-old man developed abdominal pain and the frequency of severe abdominal pain steadily increased to once a month. He was therefore admitted to our hospital. Abdominal CT showed bowel obstruction. It revealed transient stenosis in the small intestine. There were no symptoms such as fever or weight loss, it seemed unlikely that the patient had inflammatory bowel disease. Considering the history of recurrent abdominal pain, Familial Mediterranean Fever (FMF) was considered. As a result, a genetic analysis revealed mutations in exons 3 and 8 of the MEFV gene. We herein report the first known case of FMF with transient small bowel stenosis in Japan.

Keywords: Familial Mediterranean fever; colchicine; inflammatory bowel disease; small bowel stenosis.

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Conflict of interest statement

The authors state that they have no Conflict of Interest (COI).

Figures

Figure 1.
Figure 1.
An abdominal X-ray film obtained on admission. Air-fluid levels are noted in the small bowel.
Figure 2.
Figure 2.
An abdominal CT scan obtained on admission. Slight dilation of the intestinal tract and accumulation of fluid are noted. Part of the intestinal tract has formed a loop, suggesting the mechanism of obstruction.
Figure 3.
Figure 3.
A showed contrast-enhanced image through the ileus tube. Stenosis of the small bowel is revealed. B showed contrast-enhanced image through the ileus tube 3 days after A. The previous small bowel stenosis has resolved.
Figure 4.
Figure 4.
Clinical Course.
See this image and copyright information in PMC

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