Practical guidance for the use of cyclosporine ophthalmic solutions in the management of dry eye disease
- PMID: 31308620
- PMCID: PMC6612764
- DOI: 10.2147/OPTH.S184412
Practical guidance for the use of cyclosporine ophthalmic solutions in the management of dry eye disease
Abstract
Dry eye disease (DED) is a multifactorial disease of ocular surface and tear film, and is a common disorder treated by eye care providers. It is well established that ocular surface inflammation has an important role in the pathophysiology of DED and that anti-inflammatory cyclosporine A (CsA) improves the treatment outcomes of most patients with DED. The purpose of this review is to provide guidance for practitioners in the use of topical CsA for the management of DED to improve patient satisfaction and the quality of life.
Keywords: cyclosporine A; dry eye disease; keratoconjunctivitis sicca.
Conflict of interest statement
SEW was a consultant for Allergan in developing and implementing the phase III clinical trials for Restasis. The authors report no other conflicts of interest in this work.
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References
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- Dana R, Bradley JL, Guerin A, et al. Estimated prevalence and incidence of dry eye disease based on coding analysis of a large, all-age United States health care system. Am J Ophthalmol. 2019;202:47–54. - PubMed
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