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Case Reports
. 2019 May 2;11(5):e4590.
doi: 10.7759/cureus.4590.

Lithium-induced Hyperparathyroidism and Hypercalcemia

Srikanth Naramala  1 , Hussain Dalal  2 , Sreedhar Adapa  3 , Amir Hassan  4 , Venu Madhav Konala  5
Affiliations
Case Reports

Lithium-induced Hyperparathyroidism and Hypercalcemia

Srikanth Naramala et al. Cureus. .

Abstract

Lithium is one of the mainstays of treatment for bipolar disorder. Chronic lithium therapy can rarely lead to hypercalcemia secondary to lithium-induced hyperparathyroidism. We present a 66-year-old female patient with bipolar disorder on lithium therapy presenting with hypercalcemia. We discussed the pathophysiology and management of hyperparathyroidism and hypercalcemia in patients on chronic lithium therapy.

Keywords: hypercalcemia; hyperparathyroidism; lithium.

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Conflict of interest statement

The authors have declared that no competing interests exist.

Figures

Figure 1
Figure 1. Parathyroid scan showing uptake in all sites at 10 minutes (top two images) and a left-sided adenoma at four hours (bottom two images) - washout over time of sestamibi from the normal PTH tissue more rapid than a PTH adenoma. Persistent uptake in the left PTH area suggesting an adenoma on the four-hour delayed scan.
PTH: parathyroid hormone
See this image and copyright information in PMC

References

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