Efficacy of Azithromycin in Treatment of Acne Vulgaris: A Mini Review

doi:10.29252/wjps.8.2.127

Review

. 2019 May;8(2):127-134.

doi: 10.29252/wjps.8.2.127.

Efficacy of Azithromycin in Treatment of Acne Vulgaris: A Mini Review

Sina Kardeh^{1

2

3

4}, Nasrin Saki², Farideh Jowkar², Bahareh Kardeh⁵, Seyed Arman Moein^{1

3}, Mohammad Hossein Khorraminejad-Shirazi^{1

3}

Affiliations

¹ Cellular and Molecular Medicine Student Research Group, School of Medicine, Shiraz University of Medical Science, Shiraz, Iran.
² Molecular Dermatology Research Center, Department of Dermatology, Shiraz University of Medical Sciences, Shiraz, Iran.
³ Student Research Committee, Shiraz University of Medical Sciences, Shiraz, Iran.
⁴ Burn and Wound Healing Research Center, Division of Plastic and Reconstructive Surgery, Department of Surgery, Shiraz University of Medical Sciences, Shiraz, Iran.
⁵ Bone and Joint Diseases Research Center, Clinical Neurology Research Center, Shiraz University of Medical Sciences, Shiraz, Iran.

PMID: 31309049
PMCID: PMC6620802
DOI: 10.29252/wjps.8.2.127

Review

Efficacy of Azithromycin in Treatment of Acne Vulgaris: A Mini Review

Sina Kardeh et al. World J Plast Surg. 2019 May.

. 2019 May;8(2):127-134.

doi: 10.29252/wjps.8.2.127.

Authors

Sina Kardeh^{1

2

3

4}, Nasrin Saki², Farideh Jowkar², Bahareh Kardeh⁵, Seyed Arman Moein^{1

3}, Mohammad Hossein Khorraminejad-Shirazi^{1

3}

Affiliations

¹ Cellular and Molecular Medicine Student Research Group, School of Medicine, Shiraz University of Medical Science, Shiraz, Iran.
² Molecular Dermatology Research Center, Department of Dermatology, Shiraz University of Medical Sciences, Shiraz, Iran.
³ Student Research Committee, Shiraz University of Medical Sciences, Shiraz, Iran.
⁴ Burn and Wound Healing Research Center, Division of Plastic and Reconstructive Surgery, Department of Surgery, Shiraz University of Medical Sciences, Shiraz, Iran.
⁵ Bone and Joint Diseases Research Center, Clinical Neurology Research Center, Shiraz University of Medical Sciences, Shiraz, Iran.

PMID: 31309049
PMCID: PMC6620802
DOI: 10.29252/wjps.8.2.127

Abstract

Background: Antibiotics are commonly used in the treatment of acne vulgaris. Considering the rise of antibiotic resistance, alternative medications may be used in the main anti-acne armamentarium. The aim of this study was to investigate the efficacy of oral azithromycin in the treatment of acne vulgaris.

Methods: Database searches were performed in PubMed and Scopus using the keywords "azithromycin" and "acne".

Results: Azithromycin 500 mg once daily for 3 days per week or in cycles of 10 days for 12 weeks are the most commonly used regimens.

Conclusion: Available experimental data suggest that oral azithromycin is an effective and well-tolerated option for treatment of acne vulgaris.

Keywords: Acne vulgaris; Azithromycin; Doxycycline; Tetracycline; Treatment.

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Conflict of interest statement

The authors declare no conflict of interest.

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References

1. Dawson AL, Dellavalle RP. Acne vulgaris. BMJ. 2013;346:f2634. - PubMed
1. Rzany B, Kahl C. [Epidemiology of acne vulgaris] J Dtsch Dermatol Ges. 2006;4:8–9. - PubMed
1. Williams HC, Dellavalle RP, Garner S. Acne vulgaris. Lancet. 2012;379:361–72. - PubMed
1. Magin P, Pond D, Smith W, Watson A. A systematic review of the evidence for ‘myths and misconceptions’ in acne management: diet, face-washing and sunlight. Fam Pract. 2005;22:62–70. - PubMed
1. Hassanzadeh P, Bahmani M, Mehrabani D. Bacterial resistance to antibiotics in acne vulgaris: an in vitro study. Indian J Dermatol. 2008;53:122–4. - PMC - PubMed

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[1] Dawson AL, Dellavalle RP. Acne vulgaris. BMJ. 2013;346:f2634. - PubMed

[2] Dawson AL, Dellavalle RP. Acne vulgaris. BMJ. 2013;346:f2634. - PubMed

[3] Rzany B, Kahl C. [Epidemiology of acne vulgaris] J Dtsch Dermatol Ges. 2006;4:8–9. - PubMed

[4] Rzany B, Kahl C. [Epidemiology of acne vulgaris] J Dtsch Dermatol Ges. 2006;4:8–9. - PubMed

[5] Williams HC, Dellavalle RP, Garner S. Acne vulgaris. Lancet. 2012;379:361–72. - PubMed

[6] Williams HC, Dellavalle RP, Garner S. Acne vulgaris. Lancet. 2012;379:361–72. - PubMed

[7] Magin P, Pond D, Smith W, Watson A. A systematic review of the evidence for ‘myths and misconceptions’ in acne management: diet, face-washing and sunlight. Fam Pract. 2005;22:62–70. - PubMed

[8] Magin P, Pond D, Smith W, Watson A. A systematic review of the evidence for ‘myths and misconceptions’ in acne management: diet, face-washing and sunlight. Fam Pract. 2005;22:62–70. - PubMed

[9] Hassanzadeh P, Bahmani M, Mehrabani D. Bacterial resistance to antibiotics in acne vulgaris: an in vitro study. Indian J Dermatol. 2008;53:122–4. - PMC - PubMed

[10] Hassanzadeh P, Bahmani M, Mehrabani D. Bacterial resistance to antibiotics in acne vulgaris: an in vitro study. Indian J Dermatol. 2008;53:122–4. - PMC - PubMed

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Efficacy of Azithromycin in Treatment of Acne Vulgaris: A Mini Review

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Efficacy of Azithromycin in Treatment of Acne Vulgaris: A Mini Review

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