New models show gut-brain transmission of Parkinson disease pathology

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Comment

Heather Wood. Nat Rev Neurol. 2019 Sep.

. 2019 Sep;15(9):491.

doi: 10.1038/s41582-019-0241-x.

No abstract available

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Evidence for bidirectional and trans-synaptic parasympathetic and sympathetic propagation of alpha-synuclein in rats.
Van Den Berge N, Ferreira N, Gram H, Mikkelsen TW, Alstrup AKO, Casadei N, Tsung-Pin P, Riess O, Nyengaard JR, Tamgüney G, Jensen PH, Borghammer P. Van Den Berge N, et al. Acta Neuropathol. 2019 Oct;138(4):535-550. doi: 10.1007/s00401-019-02040-w. Epub 2019 Jun 26. Acta Neuropathol. 2019. PMID: 31254094 Free PMC article.
Transneuronal Propagation of Pathologic α-Synuclein from the Gut to the Brain Models Parkinson's Disease.
Kim S, Kwon SH, Kam TI, Panicker N, Karuppagounder SS, Lee S, Lee JH, Kim WR, Kook M, Foss CA, Shen C, Lee H, Kulkarni S, Pasricha PJ, Lee G, Pomper MG, Dawson VL, Dawson TM, Ko HS. Kim S, et al. Neuron. 2019 Aug 21;103(4):627-641.e7. doi: 10.1016/j.neuron.2019.05.035. Epub 2019 Jun 26. Neuron. 2019. PMID: 31255487 Free PMC article.