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. 2019 Mar 15;6(3):ofz071.
doi: 10.1093/ofid/ofz071. eCollection 2019 Mar.

Estimation of the Incidence of Guillain-Barré Syndrome During Pregnancy in the United States

Tanya R Myers  1 , Natalie L McCarthy  1 , Lakshmi Panagiotakopoulos  1 , Saad B Omer  2   3
Affiliations

Estimation of the Incidence of Guillain-Barré Syndrome During Pregnancy in the United States

Tanya R Myers et al. Open Forum Infect Dis. .

Abstract

Guillain-Barré syndrome (GBS) is an adverse event of interest after vaccination, yet few data are available for background rates during pregnancy. We confirmed 2 cases of incident GBS and estimated an incidence of 2.8 confirmed GBS cases per million person-years (95% confidence interval, 0.5-9.3), indicating rare occurrence. Our findings will help inform safety assessments of Zika vaccines in pregnant populations.

Keywords: Guillain-Barré syndrome; Vaccine Safety Datalink; pregnancy.

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