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. 2019 Nov;16(11):1456-1459.
doi: 10.1513/AnnalsATS.201904-328RL.

Fulvestrant for the Treatment of Pulmonary Arterial Hypertension

Steven M Kawut  1 , Diane Pinder  1 , Nadine Al-Naamani  1 , Amber McCormick  1 , Harold I Palevsky  1 , Jason Fritz  1 , K Akaya Smith  1 , Jeremy A Mazurek  1 , Margaret F Doyle  2 , Margaret R MacLean  3 , Angela DeMichele  1 , David A Mankoff  1
Affiliations

Fulvestrant for the Treatment of Pulmonary Arterial Hypertension

Steven M Kawut et al. Ann Am Thorac Soc. 2019 Nov.
No abstract available

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Figures

Figure 1.
Figure 1.
Hematopoietic progenitor cells (expressed as percentage of peripheral blood mononuclear cells [PBMCs]) before and after fulvestrant.
See this image and copyright information in PMC

References

    1. Ventetuolo CE, Baird GL, Barr RG, Bluemke DA, Fritz JS, Hill NS, et al. Higher estradiol and lower dehydroepiandrosterone-sulfate levels are associated with pulmonary arterial hypertension in men. Am J Respir Crit Care Med. 2016;193:1168–1175. - PMC - PubMed
    1. Baird GL, Archer-Chicko C, Barr RG, Bluemke DA, Foderaro AE, Fritz JS, et al. Lower DHEA-S levels predict disease and worse outcomes in post-menopausal women with idiopathic, connective tissue disease- and congenital heart disease-associated pulmonary arterial hypertension Eur Respir J 2018511800467. - PMC - PubMed
    1. Wright AF, Ewart MA, Mair K, Nilsen M, Dempsie Y, Loughlin L, et al. Oestrogen receptor α in pulmonary hypertension. Cardiovasc Res. 2015;106:206–216. - PMC - PubMed
    1. Asosingh K, Aldred MA, Vasanji A, Drazba J, Sharp J, Farver C, et al. Circulating angiogenic precursors in idiopathic pulmonary arterial hypertension. Am J Pathol. 2008;172:615–627. - PMC - PubMed
    1. Masuda H, Kalka C, Takahashi T, Yoshida M, Wada M, Kobori M, et al. Estrogen-mediated endothelial progenitor cell biology and kinetics for physiological postnatal vasculogenesis. Circ Res. 2007;101:598–606. - PubMed

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