Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Case Reports
. 2019 Jan-Mar;14(1):42-45.
doi: 10.4103/jpn.JPN_45_18.

Organophosphorus-Induced Toxic Myeloneuropathy: Series of Three Adolescent Patients with Short Review

Priyabrata Nayak  1 , Ashok K Mallick  1 , Shubhankar Mishra  1 , Debasish Panigrahy  1
Affiliations
Case Reports

Organophosphorus-Induced Toxic Myeloneuropathy: Series of Three Adolescent Patients with Short Review

Priyabrata Nayak et al. J Pediatr Neurosci. 2019 Jan-Mar.

Abstract

Organophosphate (OP) poisoning is the most common poisoning in India, accounting for almost half of the hospital admissions due to poisoning. Delayed neuropathy is initiated by an attack on a nervous tissue esterase. Although uncommon, delayed neurotoxicity has been consistently reported in literature. This mechanism is implicated not only in damaging peripheral nervous system but also in causing central processes leading to myelopathy. We report a series of three adolescent patients who came to our hospital with delayed neurological manifestations of organophosphorus poisoning, which came out to be OP-induced myeloneuropathy after detailed analysis and evaluation.

Keywords: Myeloneuropathy; OPIDN; nerve conduction velocity; organophosphorus.

PubMed Disclaimer

Conflict of interest statement

There are no conflicts of interest.

References

    1. Singh S, Sharma N. Neurological syndromes following organophosphate poisoning. Neurol India. 2000;48:308–13. - PubMed
    1. Abou-Donia MB. Organophosphorus ester-induced chronic neurotoxicity. Arch Environ Health. 2003;58:484–97. - PubMed
    1. Moretto A, Lotti M. Poisoning by organophosphorus insecticides and sensory neuropathy. J Neurol Neurosurg Psychiatry. 1998;64:463–8. - PMC - PubMed
    1. Aygun D, Doganay Z, Altintop L, Guven H, Onar M, Deniz T, et al. Serum acetylcholinesterase and prognosis of acute organophosphate poisoning. J Toxicol Clin Toxicol. 2002;40:903–10. - PubMed
    1. Samuel J, Thomas K, Jeyaseelan L, Peter JV, Cherian AM. Incidence of intermediate syndrome in organophosphorous poisoning. J Assoc Physicians India. 1995;43:321–3. - PubMed

Publication types