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. 2019 Jul 18;14(7):e0219689.
doi: 10.1371/journal.pone.0219689. eCollection 2019.

Secular trends in HIV/AIDS mortality in China from 1990 to 2016: Gender disparities

Disi Gao  1 , Zhiyong Zou  1 , Bin Dong  1 , Wenjing Zhang  1 , Tianqi Chen  1 , Wenxin Cui  1 , Yinghua Ma  1
Affiliations

Secular trends in HIV/AIDS mortality in China from 1990 to 2016: Gender disparities

Disi Gao et al. PLoS One. .

Abstract

Objectives: HIV/AIDS has become the leading cause of death by infectious disease in China since 2009. However, the trend of gender disparities in HIV/AIDS has not been reported in China since 1990. Our study aimed to explore the secular trend of HIV/AIDS mortality in China from 1990 to 2016 and to identify its gender disparities over the past 27 years.

Method: The mortality data of HIV/AIDS were obtained from the Global Burden of Disease Study 2016 (GBD 2016). Logistic regression was used to estimate the prevalence odds ratio (POR) of gender for HIV/AIDS mortality in different surveys.

Results: The standardized mortality of HIV/AIDS in China rose dramatically from 0.33 per 100,000 people in 1990 to 2.50 per 100,000 people in 2016. The rate of HIV/AIDS mortality increased more quickly in men than in women, and the sex gap of mortality of HIV/AIDS widened. By 2016, the HIV/AIDS mortality in men was 3 times that in women and was 5.74 times that in women within the 75- to 79-year-old age group.

Conclusions: The mortality of HIV/AIDS in China is increasing, with a widening gender disparity. It is critical for policymakers to develop policies to eliminate these disparities and to ensure that everyone can live a long life in full health.

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Conflict of interest statement

The authors have declared that no competing interests exist.

Figures

Fig 1
Fig 1. CDR and SMR trends in HIV/AIDS in the 10- to 79-year-old age group from 1990 to 2016.
The standardized mortality rate (SMR) of the 10- to 79-year-old age group was based on the distribution of males and females in the 2010 census data.
Fig 2
Fig 2
Age-specific mortality of HIV/AIDS and 95% uncertainty interval (UI) among males (left figure) and females (right figure) aged 10 to 79 years old from 1990 to 2016. Increasing trends were observed in both males and females, but the increase among females was less than that among males.
Fig 3
Fig 3. Changes in the ratio of HIV/AIDS mortality of males to females.
From 2001 to 2016, the gap between male and female standardized mortality increased significantly.
Fig 4
Fig 4. Age-specific HIV/AIDS mortality risk ratios (RRs) of males compared with females in different years in China.
The gender difference in HIV/AIDS mortality was readily apparent and increased gradually with age.
See this image and copyright information in PMC

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