Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2019 Sep 1:380:175-186.
doi: 10.1016/j.heares.2019.07.003. Epub 2019 Jul 7.

Early phase trials of novel hearing therapeutics: Avenues and opportunities

Anne G M Schilder  1 , Matthew P Su  2 , Rishi Mandavia  3 , Caroline R Anderson  2 , Evie Landry  4 , Tanjinah Ferdous  2 , Helen Blackshaw  2
Affiliations
Review

Early phase trials of novel hearing therapeutics: Avenues and opportunities

Anne G M Schilder et al. Hear Res. .

Abstract

Novel hearing therapeutics are rapidly progressing along the innovation pathway and into the clinical trial domain. Because these trials are new to the hearing community, they come with challenges in terms of trial design, regulation and delivery. In this paper, we address the key scientific and operational issues and outline the opportunities for interdisciplinary and international collaboration these trials offer. Vital to the future successful implementation of these therapeutics is to evaluate their potential for adoption into healthcare systems, including consideration of their health economic value. This requires early engagement with all stakeholder groups along the hearing innovation pathway.

Keywords: Aetiology; Clinical trial; Diagnosis; Genetics; Hearing; Therapeutics.

PubMed Disclaimer

Publication types