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. 1987;22(4):491-6.

Elimination of UV-resistance inducing effect of R46 R factor by 5-fluorouracil

I Francia  1 , Z Hernádi, M Szabolcs, F Hernádi
Affiliations
  • PMID: 3132007

Elimination of UV-resistance inducing effect of R46 R factor by 5-fluorouracil

I Francia et al. Acta Biochim Biophys Hung. 1987.

Abstract

R-factor curing capacity of 5-fluorouracil (5-FU) was studied. Well detectable increase in UV-resistance was found in E. coli K12 AB1157 strain and its recB-, recC-, recF- mutants harbouring R46 R-factor. After treatment with 5-FU, these strains lost not only the antibiotic resistance coded for R46 R-factor but their UV-radioresistance, as well.

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