Influence of Fusion on the Behavior of Adjacent Disc Arthroplasty in Contiguous 2-Level Hybrid Surgery In Vivo

Abstract

Objective: To investigate whether the behavior of disc arthroplasty in 2-level hybrid surgery (HS) was affected by adjacent fusion in vivo compared with cervical disc arthroplasty (CDA) alone.

Methods: Seventy-nine patients undergoing either a 1-level CDA or contiguous 2-level HS were retrospectively reviewed. Radiologic assessments included segmental lordosis (SL), intervertebral disc height (IDH), changes in SL and IDH, range of motion (ROM) of the disc replacement and its adjacent segments, migration and subsidence of the prosthesis, heterotopic ossification (HO), and adjacent segment degeneration (ASD) adjacent to the arthroplasty level. Clinical features and outcome scores were also recorded.

Results: Compared with 1-level CDA, the increased SL and IDH immediately after surgery in 2-level HS were more likely to be lost throughout the follow-up period. However, both groups generally maintained the SL and IDH of the arthroplasty segment postoperatively. Two-level HS did not exhibit hypermobility of the disc prosthesis and preserved preoperative ROM of the adjacent segment of the device. The HS group showed adverse effects on the prosthesis stability, but there was no significant difference in the number of cases of obvious migration or subsidence between the groups. The differences in HO, ASD, and clinical outcomes between the groups were not significant at the final follow-up.

Conclusions: Although the fusion in 2-level HS partially affected the behavior of adjacent disc arthroplasty compared with CDA alone, it did not cause severe complications and adverse clinical outcomes. However, large-scale and long follow-up trials are warranted.

Keywords: Cervical disc arthroplasty; Complications; Hybrid construct; Multilevel cervical degenerative disc disease; Prosthetic behavior; Radiography.