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Case Reports
. 1988;14(3):236-7.
doi: 10.1007/BF00717997.

Hemofiltration clearance of flecainide in a patient with acute renal failure

A Borgeat  1 , J Biollaz, B Freymond, M Bayer-Berger, R Chiolero
Affiliations
Case Reports

Hemofiltration clearance of flecainide in a patient with acute renal failure

A Borgeat et al. Intensive Care Med. 1988.

Abstract

Flecainide, a new antiarrhythmic drug, has been shown not no be removed to a significant extent by hemodialysis or peritoneal dialysis, in spite of a high renal clearance. Its systemic and hemofiltrate clearances, measured in a patient under continuous hemofiltration, were 402 and 19.7 ml/min respectively. The clearance ratio of less than 5% makes the contribution of hemofiltration to the elimination of flecainide clinically negligible.

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