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. 1988 Mar-Apr;19(2):81-94.

International experience with NORPLANT and NORPLANT-2 contraceptives

I Sivin  1
Affiliations
  • PMID: 3132758

International experience with NORPLANT and NORPLANT-2 contraceptives

I Sivin. Stud Fam Plann. 1988 Mar-Apr.

Abstract

Experience encompassing more than 20,000 woman-years of use of NORPLANT capsules and 6,000 woman-years of trials of NORPLANT-2 rods is reviewed. Implant contraception repeatedly has been associated with low pregnancy rates and high continuation rates through five full years of use. Weight has proved to be a factor related to effectiveness. Women weighing less than 50 kg experienced cumulative five-year pregnancy rates well below 1 per 100, whereas the overall cumulative rate has been 3.5 per 100. Medical events reported during use that have led to discontinuation are analyzed from four large data sets.

PIP: Experience encompassing more than 20,000 woman-years of use of NORPLANT capsules and 6000 woman-years of trials of NORPLANT-2 rods is reviewed. Implant contraception repeatedly has been associated with low pregnancy rates and high continuation rates through 5 years of use. Weight has proved to be a factor related to effectiveness. Women weighing less than 50 kg experienced cumulative 5-year pregnancy rates well below 1 per 100, whereas the overall cumulative rate has been 3.5 per 100. Analysis is provided of medical events that have led to discontinuation, based on 4 large data sets.

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