Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2019 Oct;14(4):328-337.
doi: 10.1177/1556264619862467. Epub 2019 Jul 22.

Attitudes Regarding Enrollment in a Genetic Research Project: An Informed Consent Simulation Study Comparing Views of People With Depression, Diabetes, and Neither Condition

Jane Paik Kim  1 , Katie Ryan  1 , Laura Weiss Roberts  1
Affiliations

Attitudes Regarding Enrollment in a Genetic Research Project: An Informed Consent Simulation Study Comparing Views of People With Depression, Diabetes, and Neither Condition

Jane Paik Kim et al. J Empir Res Hum Res Ethics. 2019 Oct.

Abstract

In this study, participants with a self-reported history of depression, diabetes, or no illness underwent a simulated informed consent process for a hypothetical genetic study related to depression or diabetes. Participants completed a survey assessing their perceived understanding of the research process, perceptions of its risks and benefits, their satisfaction with the informed consent process, and their readiness to make a hypothetical enrollment decision. All participants indicated strong readiness to make an enrollment decision regarding the research characterized in the simulation. Participants reported understanding the consent process relatively well and being generally satisfied with it. Greater concerns were expressed regarding psychosocial risks than biological risks for genetic studies on mental disorders. Our study documented positive attitudes toward volunteering for research that involved the collection of genetic data.

Keywords: attitudes; depression; diabetes; genetics; informed consent; research participation.

PubMed Disclaimer

Figures

Figure 1
Figure 1
Study Design
Figure 2
Figure 2
Perceived benefits and concerns of genetic studies in general
See this image and copyright information in PMC

Similar articles

See all similar articles

Cited by

References

    1. Barata PC, Gucciardi E, Ahmad F, Steward DE. 2006. Cross-cultural perspectives on research participation and informed consent. Soc Sci Med 62:479–490. - PubMed
    1. Calnan M, Montaner D, and Horne R 2005. How acceptable are innovative health-care technologies? A survey of public beliefs and attitudes in England and Wales. Social Science & Medicine 60: 1937–1948. - PubMed
    1. Candilis PJ, Fletcher KE, Geppert CM, Lidz CW, and Appelbaum PS 2008. A direct comparison of research decision-making capacity: schizophrenia/schizoaffective, medically ill, and non-ill subjects. Schizophrenia Research 99(1–3): 350–8. - PMC - PubMed
    1. Carpenter WT Jr., Gold JM, Lahti AC, et al. 2000. Decisional capacity for informed consent in schizophrenia research. Archives of General Psychiatry 57(6): 533–8. - PubMed
    1. Cho MK, Magnus D, Constantine M, et al. 2015. Attitudes toward risk and informed consent for research on medical practices: a cross-sectional study. Ann Intern Med 162:690–696 - PMC - PubMed

Publication types

LinkOut - more resources