Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Comment
. 2019 Sep;9(9):1148-1149.
doi: 10.1158/2159-8290.CD-NB2019-083. Epub 2019 Jul 22.

TCR Gene Therapy Improves AML Prognosis

No authors listed
Comment

TCR Gene Therapy Improves AML Prognosis

No authors listed. Cancer Discov. 2019 Sep.

Abstract

T cells engineered to express a receptor specific for Wilms tumor antigen 1 helped prevent relapse in a small trial of patients with acute myeloid leukemia who had received an allogeneic stem-cell transplant.

PubMed Disclaimer

Comment on

  • T cell receptor gene therapy targeting WT1 prevents acute myeloid leukemia relapse post-transplant.
    Chapuis AG, Egan DN, Bar M, Schmitt TM, McAfee MS, Paulson KG, Voillet V, Gottardo R, Ragnarsson GB, Bleakley M, Yeung CC, Muhlhauser P, Nguyen HN, Kropp LA, Castelli L, Wagener F, Hunter D, Lindberg M, Cohen K, Seese A, McElrath MJ, Duerkopp N, Gooley TA, Greenberg PD. Chapuis AG, et al. Nat Med. 2019 Jul;25(7):1064-1072. doi: 10.1038/s41591-019-0472-9. Epub 2019 Jun 24. Nat Med. 2019. PMID: 31235963 Free PMC article.

LinkOut - more resources