Inflated performance measures in enhancer-promoter interaction-prediction methods

Fan Cao¹, Melissa J Fullwood^{2

3

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Affiliations

¹ Cancer Science Institute of Singapore, National University of Singapore, Singapore, Singapore.
² Cancer Science Institute of Singapore, National University of Singapore, Singapore, Singapore. mfullwood@ntu.edu.sg.
³ School of Biological Sciences, Nanyang Technological University, Singapore, Singapore. mfullwood@ntu.edu.sg.
⁴ Institute of Molecular and Cell Biology, Agency for Science, Technology and Research (A*STAR), Singapore, Singapore. mfullwood@ntu.edu.sg.

Comment

Fan Cao et al. Nat Genet. 2019 Aug.

. 2019 Aug;51(8):1196-1198.

doi: 10.1038/s41588-019-0434-7.

Fan Cao¹, Melissa J Fullwood^{2

3

4}

¹ Cancer Science Institute of Singapore, National University of Singapore, Singapore, Singapore.
² Cancer Science Institute of Singapore, National University of Singapore, Singapore, Singapore. mfullwood@ntu.edu.sg.
³ School of Biological Sciences, Nanyang Technological University, Singapore, Singapore. mfullwood@ntu.edu.sg.
⁴ Institute of Molecular and Cell Biology, Agency for Science, Technology and Research (A*STAR), Singapore, Singapore. mfullwood@ntu.edu.sg.

No abstract available

Comment in

Reply to 'Inflated performance measures in enhancer-promoter interaction-prediction methods'.
Cao Q, Yip KY. Cao Q, et al. Nat Genet. 2019 Aug;51(8):1201-1202. doi: 10.1038/s41588-019-0452-5. Nat Genet. 2019. PMID: 31332376 No abstract available.
Reply to 'Inflated performance measures in enhancer-promoter interaction-prediction methods'.
Whalen S, Pollard KS. Whalen S, et al. Nat Genet. 2019 Aug;51(8):1198-1200. doi: 10.1038/s41588-019-0473-0. Nat Genet. 2019. PMID: 31332377 No abstract available.

Enhancer-promoter interactions are encoded by complex genomic signatures on looping chromatin.
Whalen S, Truty RM, Pollard KS. Whalen S, et al. Nat Genet. 2016 May;48(5):488-96. doi: 10.1038/ng.3539. Epub 2016 Apr 4. Nat Genet. 2016. PMID: 27064255 Free PMC article.