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. 2019 Jun;36(3):365-368.
doi: 10.5114/ada.2019.85643. Epub 2019 Jun 19.

Congenital multiple juvenile xanthogranuloma

Adam Cichewicz  1 , Agnieszka Białecka  1 , Kaja Męcińska-Jundziłł  1 , Urszula Adamska  1 , Marcin Białecki  2 , Izabela Neska-Długosz  3 , Dariusz Grzanka  3 , Rafał Czajkowski  1
Affiliations

Congenital multiple juvenile xanthogranuloma

Adam Cichewicz et al. Postepy Dermatol Alergol. 2019 Jun.
No abstract available

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Conflict of interest statement

The authors declare no conflict of interest.

Figures

Figure 1
Figure 1
Skin lesions on the right forearm, in the area of the right iliac ala and on the third toe of the left foot at the admission to the Department of Dermatology (A–C). The same skin lesions 1 month later (D–F)
Figure 2
Figure 2
A – Histopathological examination of a skin sample taken from the right iliac ala, H + E, magn. 4×. Dense histiocytic proliferation in the papillary and reticular dermis. Epidermis lining the skin thin, with focally elongated rete ridges. B – HE, magn. 10×. Foamy histiocytes and giant cells dominating in the infiltrate. Some giant cells are of the Touton giant cell type (giant cells seen in lesions with high lipid content). C – Microscopic slide, HE, magn. 10–20×. Abundant eosinophils among foamy histiocytes. No mitotic figures. D – H + E, magn. 40×. Touton giant cell (xanthelasmic giant cell) with a characteristic ring of multiple nuclei surrounding a central homogenous eosinophilic cytoplasm, while a foamy, pale cytoplasm surrounds the nuclei
See this image and copyright information in PMC

References

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