Thiol-sensitive promoters of Escherichia coli
- PMID: 3133362
- PMCID: PMC211285
- DOI: 10.1128/jb.170.7.3291-3293.1988
Thiol-sensitive promoters of Escherichia coli
Abstract
Mu dX(lac) insertion mutants of Escherichia coli CSH50 in which the expression of the lacZ gene was sensitive to the presence of exogenous 1-thioglycerol or dithiothreitol were isolated. Both stimulatory and inhibitory mutants were found. The existence of several thiol-sensitive promoters suggests that exogenous thiols may provoke global stress responses in E. coli.
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