Craniosynostosis
- PMID: 31335086
- Bookshelf ID: NBK544366
Craniosynostosis
Excerpt
Craniosynostosis occurs due to the premature in-utero fusion of one or more cranial sutures. These sutures allow for passage through the birth canal and, later in development, allow the expansion and growth of the underlying brain. When these sutures close prematurely, the head shape becomes altered depending on the sutures involved. Most cases involve a single suture and are classified as non-syndromic. However, Crouzon, Pfeiffer, and Apert syndromes have been associated with multi-sutural craniosynostosis. The treatment of craniosynostosis involves surgical intervention to unlock the fused sutures, ensuring unrestricted brain development and correcting cosmetic deformities.
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Sections
- Continuing Education Activity
- Introduction
- Etiology
- Epidemiology
- Pathophysiology
- History and Physical
- Evaluation
- Treatment / Management
- Differential Diagnosis
- Treatment Planning
- Prognosis
- Complications
- Consultations
- Deterrence and Patient Education
- Pearls and Other Issues
- Enhancing Healthcare Team Outcomes
- Review Questions
- References
References
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- Hersh DS, Hughes CD. Syndromic Craniosynostosis: Unique Management Considerations. Neurosurg Clin N Am. 2022 Jan;33(1):105-112. - PubMed
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- Lajeunie E, Crimmins DW, Arnaud E, Renier D. Genetic considerations in nonsyndromic midline craniosynostoses: a study of twins and their families. J Neurosurg. 2005 Oct;103(4 Suppl):353-6. - PubMed
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