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. 1988 May;8(5):2251-6.
doi: 10.1128/mcb.8.5.2251-2256.1988.

Detection of fos protein during osteogenesis by monoclonal antibodies

P De Togni  1 , H Niman, V Raymond, P Sawchenko, I M Verma
Affiliations

Detection of fos protein during osteogenesis by monoclonal antibodies

P De Togni et al. Mol Cell Biol. 1988 May.

Abstract

We have generated monoclonal antibodies by using a synthetic peptide corresponding to amino acid positions 4 to 17 of the human fos protein. The antibodies detected both v- and c-fos proteins by immunoprecipitation, immunoblotting, and indirect immunofluorescence. The monoclonal antibodies not only identified the fos protein complex with the cellular 39-kilodalton protein, but also recognized the modified forms of the mouse, rat, and human fos proteins. In day-17 rat embryos, nuclear-staining fos protein could be identified in the cartilage by immunohistochemical staining.

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References

    1. Cell. 1987 Jun 19;49(6):835-44 - PubMed
    1. Mol Cell Biol. 1987 Feb;7(2):639-49 - PubMed
    1. Nature. 1987 Aug 20-26;328(6132):711-4 - PubMed
    1. Adv Cancer Res. 1987;49:29-52 - PubMed
    1. Cell. 1987 Nov 20;51(4):513-4 - PubMed

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