Hippo Enters the Competition
- PMID: 31336094
- DOI: 10.1016/j.devcel.2019.07.005
Hippo Enters the Competition
Abstract
In this issue of Developmental Cell, Hashimoto and Sasaki (2019) explore the role of the Hippo pathway in the establishment of naive pluripotency and cell competition in the epiblast. Their work gives insight into how the mouse embryo selects cells with the highest future potential, through the activity of YAP/TEAD.
Copyright © 2019 Elsevier Inc. All rights reserved.
Comment on
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Epiblast Formation by TEAD-YAP-Dependent Expression of Pluripotency Factors and Competitive Elimination of Unspecified Cells.Dev Cell. 2019 Jul 22;50(2):139-154.e5. doi: 10.1016/j.devcel.2019.05.024. Epub 2019 Jun 13. Dev Cell. 2019. PMID: 31204175
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