A systematic review of antiglycation medicinal plants

Abstract

Background and objectives: The present review shows a list of anti-glycation plants with their anti-glycation activity mechanisms that can attract the attention of pharmacologist for further scientific research towards finding better remedy for diabetic complications.

Materials: Google scholar, Pubmed, Web of Science and Scopus were searched. The terms were advanced glycation end products (AGEs), medicinal plants, antiglycation products.

Results: plants that studied in this review inhibit glycation in several possible mechanisms. Some of these plants inhibit the production of shiff base and amadori products. The others inhibit the generation of amadori products in the advanced phase. Some others blocked the aggregation of AGEs and some plants have antioxidant activity and reduce AGEs formation by preventing oxidation of amadori product and metal-catalyzed glucoxidation.

Conclusion: This review can help pharmacologist to find antiglycation natural substance that can be useful in treatment of diabetic complications.

Keywords: Advanced glycation end products; Antiglycation plants; Diabetes.