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. 2019 Jul 13;11(7):1587.
doi: 10.3390/nu11071587.

Cardiac Changes in Patients on Long-Term Parenteral Nutrition

Lidia Santarpia  1 , Roberta Esposito  2 , Andrea Vaccaro  3 , Lucia Alfonsi  3 , Maria Carmen Pagano  3 , Ciro Santoro  2 , Maurizio Marra  3 , Franco Contaldo  3 , Maurizio Galderisi  2 , Fabrizio Pasanisi  3
Affiliations

Cardiac Changes in Patients on Long-Term Parenteral Nutrition

Lidia Santarpia et al. Nutrients. .

Abstract

Patients with short bowel syndrome (SBS) on long-term home parenteral nutrition (HPN) chronically receive high fluid volumes directly into the right atrium (RA) through the superior vena cava. We retrospectively evaluated cardiac function measured by routine transthoracic echocardiography (TTE) in a population of 26 SBS patients on long-term HPN and compared their data on echocardiograph-derived right heart structure and function, with those of a control group of 26 patients also bearing a central venous catheter (CVC) for other reasons. Results showed that body weight and BMI were significantly higher in the control group. The echocardiographic estimate of RA pressure was higher in HPN patients than in controls (p = 0.01). An increased estimate of RA pressure indicates the need to consider TTE in the follow-up of long-term HPN patients to detect functional impairment early.

Keywords: cardiac changes; home parenteral nutrition; short bowel syndrome; transthoracic echocardiography.

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Conflict of interest statement

The authors declare no conflict of interest.

Figures

Figure 1
Figure 1
IVCmax: Inferior vena cava maximal diameter, IVCmin index: Inferior vena cava minimal diameter and estimated right atrium pressure (RAPr) in a patient with short bowel syndrome (SBS) on long-term home parenteral nutrition (HPN).
See this image and copyright information in PMC

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