Drug-induced reductions in brain amyloid-β levels may adversely affect cognition and behavior by a disruption of functional connectivity homeostasis

Affiliations

¹ Research & Development Department, Chiesi Farmaceutici, Largo Francesco Belloli 11/a, 43122 Parma, Italy.
² Department of Geriatric Psychiatry, Nathan Kline Institute, 140 Old Orangeburg Rd, Bldg 35, Orangeburg, NY 10962-1157, USA.

Comment

Bruno P Imbimbo et al. Neurodegener Dis Manag. 2019 Aug.

. 2019 Aug;9(4):189-191.

doi: 10.2217/nmt-2019-0013. Epub 2019 Jul 24.

¹ Research & Development Department, Chiesi Farmaceutici, Largo Francesco Belloli 11/a, 43122 Parma, Italy.
² Department of Geriatric Psychiatry, Nathan Kline Institute, 140 Old Orangeburg Rd, Bldg 35, Orangeburg, NY 10962-1157, USA.

No abstract available

Keywords: Alzheimer’s disease; BACE1 inhibitors; resting state functional connectivity; verubecestat.

Comment on

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