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Review
. 2019;83(3):64-72.
doi: 10.17116/neiro20198303164.

[Treatment of malignant peripheral nerve sheath tumors: case reports and a literature review]

[Article in Russian]
Affiliations
Review

[Treatment of malignant peripheral nerve sheath tumors: case reports and a literature review]

[Article in Russian]
N A Konovalov et al. Zh Vopr Neirokhir Im N N Burdenko. 2019.

Abstract

Malignant peripheral nerve sheath tumors (MPNSTs) are soft tissue sarcomas that develop from peripheral nerve sheath cells (T. Hirose, B.W. Scheithauer). These tumors are characterized by aggressive growth with an unfavorable outcome and may develop de novo or through malignant transformation of schwannomas, neurofibromas, or ganglioneuromas. MPNSTs are characterized by a rapid course and a poor prognosis. In this article, we reported cases of patients with malignant peripheral nerve tumors of the brachial plexus trunks and spinal localization.

Злокачественные опухоли оболочек периферических нервов (ЗООПН) относят к саркомам мягких тканей, которые развиваются из клеток оболочек периферических нервов (T. Hirose, B. Scheithauer). Данные опухоли характеризуются агрессивным ростом с неблагоприятным исходом и могут развиваться de novo или путем озлокачествления шванномы, нейрофибромы или ганглионевромы. В статье авторы представили 2 наблюдения с ЗООПН стволов плечевого сплетения и спинальной локализации.

Keywords: malignant neurofibroma; malignant peripheral nerve sheath tumor; neurogenic sarcoma.

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