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. 2019 Oct 1;58(40):14110-14114.
doi: 10.1002/anie.201906913. Epub 2019 Aug 21.

RhI -Catalyzed PIII -Directed C-H Bond Alkylation: Design of Multifunctional Phosphines for Carboxylation of Aryl Bromides with Carbon Dioxide

Zhuan Zhang  1 , Thierry Roisnel  1 , Pierre H Dixneuf  1 , Jean-François Soulé  1
Affiliations
Free article

RhI -Catalyzed PIII -Directed C-H Bond Alkylation: Design of Multifunctional Phosphines for Carboxylation of Aryl Bromides with Carbon Dioxide

Zhuan Zhang et al. Angew Chem Int Ed Engl. .
Free article

Abstract

We report the C-H alkylation of biarylphosphines at the ortho' position(s) with alkenes by using rhodium(I) catalysis, which provides straightforward access to a large library of multifunctionalized phosphines. Some of these modified ligands outperformed commercially available phosphines in the Pd-catalyzed carboxylation of aryl bromides with carbon dioxide in the presence of a photoredox catalyst.

Keywords: C−H functionalization; alkylation; carbon dioxide; phosphine ligands; rhodium.

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References

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