Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2019 Jul 18;63(3):306-311.
doi: 10.20945/2359-3997000000151.

Insufficient iodine intake in pregnant women in different regions of the world: a systematic review

Aline C Candido  1 , Núbia de S de Morais  1 , Luiza V Dutra  1 , Carina A Pinto  1 , Sylvia do C C Franceschini  1 , Rita de Cássia G Alfenas  1
Affiliations

Insufficient iodine intake in pregnant women in different regions of the world: a systematic review

Aline C Candido et al. Arch Endocrinol Metab. .

Erratum in

Abstract

Objective: To determine the prevalence of insufficient iodine intake in pregnant women.

Materials and methods: The search was performed in the electronic databases Medline (PubMed), Latin American and Caribbean Literature in Health Sciences (Lilacs) and Scopus. Review studies, experimental studies, those with adolescent pregnant women (< 20 years) and iodine supplementation were excluded. The selection followed the steps of identifying the articles in the databases, deleting the duplicates, and reading the titles, abstracts, and then the entire article. The search for the articles occurred in September 2017, using the descriptors "pregnant" and "iodine deficiency" NOT "supplementation" in English, Portuguese and Spanish.

Results: Thirteen articles were included, the deficiency prevalence ranged from 16.1% to 84.0%, and the median of iodine intake was insufficient in 75% of the studies. There is no classification for mild, moderate or severe levels of iodine deficiency in pregnant women, which makes it impossible to know the real dimension of the problem.

Conclusion: The high prevalence of insufficient iodine intake in pregnant women, observed worldwide, shows the need for a population classification in order to direct public policies. Arch Endocrinol Metab. 2019;63(3):306-11.

PubMed Disclaimer

Conflict of interest statement

Disclosure: no potential conflict of interest relevant to this article was reported.

Figures

Figure 1
Figure 1. Flowchart of the process of identification and selection of the articles included. Source: PRISMA (9).
See this image and copyright information in PMC

References

    1. Calvo RM, Jauniaux E, Gulbis B, Asunción M, Gervy C, Contempré B, et al. Fetal tissues are exposed to biologically relevant free thyroxine concentrations during early phases of development. J Clin Endocrinol Metab. 2002;87(4):1768-77. - PubMed
    1. Morreale de Escobar G, Obregon MJ, Escobar del Rey F. Role of thyroid hormone during early brain development. Eur J Endocrinol [Internet]. 2004;(Suppl 3):U25-37. - PubMed
    1. Teixeira D, Calhau C, Pestana D, Vicente L, Graça P. Iodo – Importância para a saúde e o papel da alimentação. Programa Nacional para a Promoção da Alimentação Saudável – Direção-Geral da Saúde; 2014.
    1. Katz PM, Leung AM, Braverman LE, Pearce EM, Tomlinson G, He X, et al. Iodine Nutrition During Pregnancy In Toronto, Canada. Endocr Pract. 2013;19(2):206-11. - PMC - PubMed
    1. Lazarus JH. Thyroid disease in relation to pregnancy: A decade of change. Clin Endocrinol (Oxf) [Internet]. 2000;53(3):265-78. - PubMed

Publication types

LinkOut - more resources