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. 2019:1:e190003.
doi: 10.20900/agmr20190003. Epub 2019 Jun 5.

Aging Well: Using Precision to Drive Down Costs and Increase Health Quality

Rhoda Au  1   2   3   4 , Marina Ritchie  4 , Spencer Hardy  4 , Ting Fang Alvin Ang  2   3   4 , Honghuang Lin  2   5
Affiliations

Aging Well: Using Precision to Drive Down Costs and Increase Health Quality

Rhoda Au et al. Adv Geriatr Med Res. 2019.

Abstract

Efforts to provide patients with individualized treatments have led to tremendous breakthroughs in healthcare. However, a precision medicine approach alone will not offset the rapid increase in prevalence and burden of chronic non-communicable illnesses that is continuing to pervade the world's aging population. With rapid advances in technology, it is now possible to collect digital metrics to assess, monitor and detect chronic disease indicators, much earlier in the disease course, potentially redefining what was previously considered asymptomatic to pre-symptomatic. Data science and artificial intelligence can drive the discovery of digital biomarkers before the emergence of overt clinical symptoms, thereby transforming the current healthcare approach from one centered on precision medicine to a more comprehensive focus on precision health, and by doing so enable the possibility of preventing disease altogether. Presented herein are the challenges to the current healthcare model and the proposition of first steps for reversing the prevailing intractable trend of rising healthcare costs and poorer health quality.

Keywords: aging; digital biomarkers; precision health.

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Conflict of interest statement

CONFLICTS OF INTEREST The authors declare that they have no conflicts of interest.

References

    1. United Nations, Department of Economic and Social Affairs, Population Division. World Population Ageing. New York (US): United Nations; 2017. ST/ESA/SER.A/408.
    1. United Nations, Department of Economic and Social Affairs, Population Division. World Population Prospects: The 2017 Revision, Key Findings and Advance Tables. New York (US): United Nations; 2017. Working Paper No.:ESA/P/WP/248.
    1. World Health Organization. Global health and aging. Geneva (Switzerland): World Health Organization; 2011. October NIH Publication No.: 11–7737. Available from: https://www.who.int/ageing/publications/global_health.pdf. Accessed 2019 May 16.
    1. Lozano R, Naghavi M, Foreman K, Lim S, Shibuya K, Aboyans V, et al. Global and regional mortality from 235 causes of death for 20 age groups in 1990 and 2010: A systematic analysis for the Global Burden of Disease Study 2010. Lancet. 2012;380(9859):2095–128. doi: 10.1016/S0140-6736(12)61728-0 - DOI - PMC - PubMed
    1. Suzman R, Beard JR, Boerma T, Chatterji S. Health in an ageing world—what do we know? Lancet. 2015;385(9967):484–6. doi: 10.1016/S0140-6736(14)61597-X - DOI - PubMed

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