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Comparative Study
. 1988 Apr;7(2):188-90.
doi: 10.1007/BF01963078.

Susceptibility of streptomycin-resistant Mycobacterium tuberculosis strains to amikacin

S E Hoffner  1 , G Källenius
Affiliations
Comparative Study

Susceptibility of streptomycin-resistant Mycobacterium tuberculosis strains to amikacin

S E Hoffner et al. Eur J Clin Microbiol Infect Dis. 1988 Apr.

Abstract

A total of 585 Mycobacterium tuberculosis strains isolated during a three-year period in Sweden were tested for in vitro susceptibility to amikacin in comparison with streptomycin. Resistance to streptomycin was seen in 27 of the isolates (4.6%). These isolates had been obtained from 22 patients, a majority of which were non-European immigrants. All but one of the streptomycin-resistant isolates were susceptible to amikacin. None of 263 streptomycin-susceptible isolates tested was resistant to amikacin. Amikacin appears to be an alternative to streptomycin in the treatment of patients with streptomycin-resistant Mycobacterium tuberculosis.

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