Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Comment
. 2019 Dec 1;200(11):1444-1446.
doi: 10.1164/rccm.201906-1159LE.

CD71- Alveolar Macrophages in Idiopathic Pulmonary Fibrosis: A Look beyond the Borders of the Disease

Affiliations
Comment

CD71- Alveolar Macrophages in Idiopathic Pulmonary Fibrosis: A Look beyond the Borders of the Disease

Ermanno Puxeddu et al. Am J Respir Crit Care Med. .
No abstract available

PubMed Disclaimer

Figures

Figure 1.
Figure 1.
Gating strategy applied for flow-cytometry analysis and individuation of BAL CD71-expressing alveolar macrophages.
Figure 2.
Figure 2.
Proportions of CD71 alveolar macrophages (AMs) in idiopathic pulmonary fibrosis (IPF) and non-IPF BAL. ILD = interstitial lung disease.

Comment in

Comment on

References

    1. Maher TM. Precision medicine in idiopathic pulmonary fibrosis. QJM. 2016;109:585–587. - PMC - PubMed
    1. Allden SJ, Ogger PP, Ghai P, McErlean P, Hewitt R, Toshner R, et al. The transferrin receptor CD71 delineates functionally distinct airway macrophage subsets during idiopathic pulmonary fibrosis. Am J Respir Crit Care Med. 2019;200:209–219. - PMC - PubMed
    1. Puxeddu E, Comandini A, Cavalli F, Pezzuto G, D’Ambrosio C, Senis L, et al. Iron laden macrophages in idiopathic pulmonary fibrosis: the telltale of occult alveolar hemorrhage? Pulm Pharmacol Ther. 2014;28:35–40. - PubMed
    1. Sangiuolo F, Puxeddu E, Pezzuto G, Cavalli F, Longo G, Comandini A, et al. HFE gene variants and iron-induced oxygen radical generation in idiopathic pulmonary fibrosis. Eur Respir J. 2015;45:483–490. - PubMed
    1. Lee J, Arisi I, Puxeddu E, Mramba LK, Amicosante M, Swaisgood CM, et al. Bronchoalveolar lavage (BAL) cells in idiopathic pulmonary fibrosis express a complex pro-inflammatory, pro-repair, angiogenic activation pattern, likely associated with macrophage iron accumulation. PLoS One. 2018;13:e0194803. - PMC - PubMed

Substances