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Case Reports
. 2019 Oct;44(10):e581-e582.
doi: 10.1097/RLU.0000000000002740.

Dynamic FET PET Imaging of a "Butterfly" IDH-Wildtype Anaplastic Astrocytoma

Norbert Galldiks  1   2   3 , Anna Brunn  4 , Gereon R Fink  1   2 , Karl-Josef Langen  2   5
Affiliations
Case Reports

Dynamic FET PET Imaging of a "Butterfly" IDH-Wildtype Anaplastic Astrocytoma

Norbert Galldiks et al. Clin Nucl Med. 2019 Oct.

Abstract

A variety of neoplastic and nonneoplastic conditions involve the corpus callosum, which may result in a "butterfly" appearance on conventional MRI. Typically, that pattern shows a bilateral and heterogeneous contrast enhancement of the lesion, occasionally with central nonenhancing areas indicating intralesional necrosis. In contrast, anaplastic gliomas may show only minimal or even a lack of contrast enhancement on MRI. We here report neuroimaging findings in a 69-year-old man with a "butterfly" pattern on dynamic FET [O-(2-[F]-fluoroethyl)-L-tyrosine] PET and the diagnosis of an anaplastic astrocytoma (WHO grade III; IDH-1/-2 wildtype, no 1p/19q co-deletion) but without typical MRI contrast enhancement.

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