Site-Programmable Transposition: Shifting the Paradigm for CRISPR-Cas Systems

Michael Chavez¹, Lei S Qi²

Affiliations

¹ Department of Bioengineering, Stanford University, Stanford, CA, USA.
² Department of Bioengineering, Stanford University, Stanford, CA, USA; Department of Chemical and Systems Biology, Stanford University, Stanford, CA, USA; ChEM-H, Stanford University, Stanford, CA, USA. Electronic address: stanley.qi@stanford.edu.

PMID: 31348878
DOI: 10.1016/j.molcel.2019.07.004

Free article

Comment

Site-Programmable Transposition: Shifting the Paradigm for CRISPR-Cas Systems

Michael Chavez et al. Mol Cell. 2019.

Free article

. 2019 Jul 25;75(2):206-208.

doi: 10.1016/j.molcel.2019.07.004.

Authors

Michael Chavez¹, Lei S Qi²

Affiliations

¹ Department of Bioengineering, Stanford University, Stanford, CA, USA.
² Department of Bioengineering, Stanford University, Stanford, CA, USA; Department of Chemical and Systems Biology, Stanford University, Stanford, CA, USA; ChEM-H, Stanford University, Stanford, CA, USA. Electronic address: stanley.qi@stanford.edu.

PMID: 31348878
DOI: 10.1016/j.molcel.2019.07.004

Abstract

Discoveries by Klompe et al. (2019) and Strecker et al. (2019) elucidate distinct CRISPR-Cas mechanisms for site-specific programmable transposition in prokaryotic organisms.

PubMed Disclaimer

Comment on

RNA-guided DNA insertion with CRISPR-associated transposases.
Strecker J, Ladha A, Gardner Z, Schmid-Burgk JL, Makarova KS, Koonin EV, Zhang F. Strecker J, et al. Science. 2019 Jul 5;365(6448):48-53. doi: 10.1126/science.aax9181. Epub 2019 Jun 6. Science. 2019. PMID: 31171706 Free PMC article.
Transposon-encoded CRISPR-Cas systems direct RNA-guided DNA integration.
Klompe SE, Vo PLH, Halpin-Healy TS, Sternberg SH. Klompe SE, et al. Nature. 2019 Jul;571(7764):219-225. doi: 10.1038/s41586-019-1323-z. Epub 2019 Jun 12. Nature. 2019. PMID: 31189177

Publication types

Actions

MeSH terms

Actions
Actions
Actions
Actions
Actions

Substances

Actions
Actions
Actions

LinkOut - more resources

Full Text Sources
- Elsevier Science
Other Literature Sources
- The Lens - Patent Citations Database

Save citation to file

Email citation

Add to Collections

Add to My Bibliography

Your saved search

Create a file for external citation management software

Your RSS Feed

Site-Programmable Transposition: Shifting the Paradigm for CRISPR-Cas Systems

Affiliations

Site-Programmable Transposition: Shifting the Paradigm for CRISPR-Cas Systems

Authors

Affiliations

Abstract

Comment on

Publication types

MeSH terms

Substances

LinkOut - more resources

Full Text Sources

Other Literature Sources