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. 2019 Aug:46:9-10.
doi: 10.1016/j.ebiom.2019.07.054. Epub 2019 Jul 23.

Emerging novel therapies against paracetamol (acetaminophen) hepatotoxicity

Hartmut Jaeschke  1
Affiliations

Emerging novel therapies against paracetamol (acetaminophen) hepatotoxicity

Hartmut Jaeschke. EBioMedicine. 2019 Aug.
No abstract available

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References

    1. Jaeschke H. Acetaminophen: dose-dependent drug hepatotoxicity and acute liver failure in patients. Dig Dis. 2015;33(4):464–471. - PMC - PubMed
    1. McGill M.R., Jaeschke H. Metabolism and disposition of acetaminophen: recent advances in relation to hepatotoxicity and diagnosis. Pharm Res. 2013 Sep;30(9):2174–2187. - PMC - PubMed
    1. Rumack B.H., Bateman D.N. Acetaminophen and acetylcysteine dose and duration: past, present and future. Clin Toxicol (Phila) 2012 Feb;50(2):91–98. - PubMed
    1. Jaeschke H., McGill M.R., Ramachandran A. Oxidant stress, mitochondria, and cell death mechanisms in drug-induced liver injury: lessons learned from acetaminophen hepatotoxicity. Drug Metab Rev. 2012 Feb;44(1):88–106. - PMC - PubMed
    1. Du K., Ramachandran A., Jaeschke H. Oxidative stress during acetaminophen hepatotoxicity: sources, pathophysiological role and therapeutic potential. Redox Biol. 2016 Dec;10:148–156. - PMC - PubMed

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