Fatality from potassium gold cyanide poisoning
- PMID: 31350229
- PMCID: PMC6663265
- DOI: 10.1136/bcr-2019-229947
Fatality from potassium gold cyanide poisoning
Abstract
While potassium cyanide poisoning has been well described, the toxicity of potassium gold cyanide is less well understood. This case describes an 84-year-old man who presented after an intentional ingestion of 0.5-1 teaspoons of potassium gold cyanide. Despite antidotal therapy, the patient rapidly developed severe lactic acidosis, multiorgan dysfunction and ultimately expired. While the patient's clinical findings were consistent with acute cyanide poisoning, a serum cyanide level was below the toxic threshold. Previous reports have suggested that gold toxicity may also contribute to the effects of potassium gold cyanide, and may have played a role in the patient's rapid decline. In addition to treatment of cyanide toxicity, management of acute gold toxicity should also be considered in potassium gold cyanide ingestion.
Keywords: emergency medicine; poisoning.
© BMJ Publishing Group Limited 2019. No commercial re-use. See rights and permissions. Published by BMJ.
Conflict of interest statement
Competing interests: None declared.
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References
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- Aitio A, Kiilunen M, Santonen T, et al. . Gold and Gold Mining: In Handbook on the Toxicology of Metals, 2015:817–43.
-
- Pradhan M, Pawar A, Chand S, et al. . Accidental cyanide poisoning from inhalation of gold polishing chemical: An unusual Case Report. J Punjab Acad Forensic Med Toxicol 2012;12:104–6.
-
- Wu ML, Tsai WJ, Ger J, et al. . Cholestatic hepatitis caused by acute gold potassium cyanide poisoning. J Toxicol Clin Toxicol 2001;39:739–43. - PubMed
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