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. 2019 Nov-Dec;34(7-8):507-512.
doi: 10.1177/1533317519865428. Epub 2019 Jul 28.

Association Between Individual Components of Metabolic Syndrome and Cognitive Function in Northeast Rural China

Xue Wang  1 , Dechun Luan  2 , Shimeng Xin  1 , Yang Liu  1 , Qian Gao  1
Affiliations

Association Between Individual Components of Metabolic Syndrome and Cognitive Function in Northeast Rural China

Xue Wang et al. Am J Alzheimers Dis Other Demen. 2019 Nov-Dec.

Abstract

Aim: The aim of this article was to examine associations between metabolic syndrome and its individual components with cognitive function among rural elderly population in northeast China.

Methods: Our study included 1047 residents aged older than 60 years in a northeast rural area. All were interviewed and data were obtained including sociodemographic and medical histories. Cognitive function was assessed by Mini-Mental State Examination. Metabolic syndrome was defined by NCEP-ATP III.

Results: After adjusted for confounding factors, metabolic syndrome was inversely associated with cognitive function (odds ratio [OR] = 1.79; 95% confidence interval [CI]: 1.06-3.01) especially in participants aged less than 70 years old (OR = 2.60; 95% CI: 1.27-5.26). In addition, participants with metabolic syndrome had worse language function, which is a part of cognitive function (OR = 2.64; 95% CI: 1.39-5.00). Individual metabolic syndrome components, especially abdominal obesity and hyperglycemia, had significant association with cognitive function (OR = 0.72, 95% CI: 0.56-0.92 and OR = 1.41; 95% CI: 1.12-1.78, respectively).

Conclusions: Abdominal obesity might be a protective factor for cognitive function. However, hyperglycemia might be a risk factor.

Keywords: MMSE; abdominal obesity; cognitive function; elderly; ·metabolic syndrome.

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Conflict of interest statement

The authors declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article.

Figures

Figure 1.
Figure 1.
Flow diagram for study.
See this image and copyright information in PMC

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