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. 2018 Oct:58:1061-1073.
doi: 10.1016/j.trf.2018.08.002. Epub 2018 Jan 22.

A pilot investigation on the effects of combination transcranial direct current stimulation and speed of processing cognitive remediation therapy on simulated driving behavior in older adults with HIV

C N Pope  1 , D Stavrinos  2 , D E Vance  3 , A J Woods  4 , T R Bell  2 , K K Ball  2 , P L Fazeli  3
Affiliations

A pilot investigation on the effects of combination transcranial direct current stimulation and speed of processing cognitive remediation therapy on simulated driving behavior in older adults with HIV

C N Pope et al. Transp Res Part F Traffic Psychol Behav. 2018 Oct.

Abstract

Cognitive impairments seen in people living with HIV (PLWH) are associated with difficulties in everyday functioning, specifically driving. This study utilized speed of processing cognitive remediation therapy (SOP-CRT) with transcranial direct current stimulation (tDCS) to gauge the feasibility and impact on simulated driving. Thirty PLWH (M age = 54.53, SD = 3.33) were randomly assigned to either: sham tDCS SOP-CRT or active tDCS SOP-CRT. Seven indicators of simulated driving performance and safety were obtained. Repeated measures ANOVAs controlling for driver's license status (valid and current license or expired/no license) revealed a large training effect on average driving speed. Participants who received active tDCS SOP-CRT showed a slower average driving speed (p = 0.020, d = 0.972) than those who received sham tDCS SOP-CRT. Non-significant small-to-medium effects were seen for driving violations, collisions, variability in lane positioning, and lane deviations. Combination tDCS SOP-CRT was found to increase indices of cautionary simulated driving behavior. Findings reveal a potential avenue of intervention and rehabilitation for improving driving safety among vulnerable at-risk populations, such as those aging with chronic disease.

Keywords: Brain simulation; HIV/AIDS; cognitive remediation therapy; driving; neuromodulation; tDCS.

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Figures

Fig. 1
Fig. 1
Study recruitment chart.
Fig. 2
Fig. 2
Interaction of time and training group on average driving speed (a) and lane deviations (b).
See this image and copyright information in PMC

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References

    1. Aarts L, & van Schagen I (2006). Driving speed and the risk of road crashes: A review. Accident Analysis & Prevention, 38(2), 215–224. doi: 10.1016/j.aap.2005.07.004 - DOI - PubMed
    1. Ahn H, Woods AJ, Kunik ME, Bhattacharjee A, Chen Z, Choi E, & Fillingim RB (2017). Efficacy of transcranial direct current stimulation over primary motor cortex (anode) and contralateral supraorbital area (cathode) on clinical pain severity and mobility performance in persons with knee osteoarthritis: An experimenter- and participant-blinded, randomized, sham-controlled pilot clinical study. Brain Stimulation, 10(5), 902–909. doi: 10.1016/j.brs.2017.05.007 - DOI - PMC - PubMed
    1. Alabama Division of STD Prevention and Control. (2014). State of Alabama HIV Surveillance 2014 Annual Report Montgomery, AL: Alabama Department of Public Health.
    1. Anstey KJ, Wood J, Lord S, & Walker JG (2005). Cognitive, sensory and physical factors enabling driving safety in older adults. Clinical Psychology Review, 25(1), 45–65. doi: 10.1016/j.cpr.2004.07.008 - DOI - PubMed
    1. Ball KK, Berch DB, Helmers KF, Jobe JB, Leveck MD, Marsiske M, . . . Willis SL (2002). Effects of cognitive training interventions with older adults: A randomized controlled trial. JAMA: The Journal of the American Medical Association, 288(18), 2271–2281. doi: 10.1001/jama.288.18.2271 - DOI - PMC - PubMed

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