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Case Reports
. 2019 Jul 4:2019:3278147.
doi: 10.1155/2019/3278147. eCollection 2019.

Anesthetic Management of Total Aortic Arch Replacement in a Myasthenia Gravis Patient under Deep Hypothermic Circulatory Arrest

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Case Reports

Anesthetic Management of Total Aortic Arch Replacement in a Myasthenia Gravis Patient under Deep Hypothermic Circulatory Arrest

Mamiko Kondo et al. Case Rep Anesthesiol. .

Abstract

The anesthetic management of myasthenia gravis patients undergoing cardiac or aortic surgery under cardiopulmonary bypass, especially with deep hypothermic circulatory arrest, is challenging. We describe a case of successful anesthetic management of a myasthenia gravis patient undergoing total arch replacement with deep hypothermic circulatory arrest under neuromuscular monitoring and complete reversal of the action of neuromuscular blocking drugs by sugammadex. The present case suggests that patients with well-controlled myasthenia gravis might be safely managed in cardiac or aortic surgery under cardiopulmonary bypass with deep hypothermic circulatory arrest.

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References

    1. Nilsson E., Meretoja O. A. Vecuronium dose—response and maintenance requirements in patients with myasthenia gravis. Anesthesiology. 1990;73(1):28–32. doi: 10.1097/00000542-199007000-00005. - DOI - PubMed
    1. Paterson I., Hood J., Russell S., Weston M., Hirech N. Mivacurium in the myasthenic patient. British Journal of Anaesthesia. 1994;73(4):494–498. doi: 10.1093/bja/73.4.494. - DOI - PubMed
    1. Barry A. E., Chaney M. A., London M. J. Anesthetic management during cardiopulmonary bypass: a systematic review. Anesthesia and Analgesia. 2015;120:749–769. - PubMed
    1. Heier T., Caldwell J. E. Impact of Hypothermia on the Response to Neuromuscular Blocking Drugs. Anesthesiology. 2006;104(5):1070–1080. doi: 10.1097/00000542-200605000-00025. - DOI - PubMed
    1. Demir T., Ugurlucan M., Bahceci F., Demir H. B., Sezer S. Coronary artery bypass grafting in a patient with myasthenia gravis. Heart Surgery Forum. 2014;17(5):E239–E241. doi: 10.1532/HSF98.2014383. - DOI - PubMed

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