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Review
. 2020 May;18(5):1015-1024.
doi: 10.1016/j.cgh.2019.07.043. Epub 2019 Jul 26.

Integrated Model for Patient-Centered Advanced Liver Disease Care

Affiliations
Review

Integrated Model for Patient-Centered Advanced Liver Disease Care

Aanand D Naik et al. Clin Gastroenterol Hepatol. 2020 May.

Abstract

Advanced liver disease (AdvLD) is a high-risk common condition with a progressive, highly morbid, and often fatal course. Despite effective treatments, there are substantial shortfalls in access to and use of evidence-based supportive and palliative care for AdvLD. Although patient-centered, chronic illness models that integrate early supportive and palliative care with curative treatments hold promise, there are several knowledge gaps that hinder development of an integrated model for AdvLD. We review these evidence gaps. We also describe a conceptual framework for a patient-centered approach that explicates key elements needed to improve integrated care. An integrated model of AdvLD would allow clinicians, patients, and caregivers to work collaboratively to identify treatments and other healthcare that best align with patients' priorities.

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Conflict of interest statement

Conflicts of interest

The authors disclose no conflicts.

Figures

Figure 1.
Figure 1.
Chronic care model applied to advance liver disease care. AdvLD, advanced liver disease
Figure 2.
Figure 2.
The integrated model for patient-centered advanced liver disease care. AdvLD, advanced liver disease

References

    1. Beste LA, Leipertz SL, Green PK, Dominitz JA, Ross D, Ioannou GN. Trends in burden of cirrhosis and hepatocellular carcinoma by underlying liver disease in US veterans, 2001–2013. Gastroenterology 2015;149:1471–1482.e5; quiz e17–18. - PubMed
    1. Kanwal F, Kramer JR, Duan Z, Yu X, White D, El-Serag HB. Trends in the burden of nonalcoholic fatty liver disease in a United States cohort of veterans. Clin Gastroenterol Hepatol 2016;14:301–308.e1-2. - PMC - PubMed
    1. D’Amico G, Garcia-Tsao G, Pagliaro L. Natural history and prognostic indicators of survival in cirrhosis: a systematic review of 118 studies. J Hepatol 2006;44:217–231. - PubMed
    1. Ratib S, Fleming KM, Crooks CJ, Aithal GP, West J. 1 and 5 year survival estimates for people with cirrhosis of the liver in England, 1998-2009: A large population study. J Hepatol 2014;60:282–289. - PubMed
    1. Volk ML, Tocco RS, Bazick J, Rakoski MO, Lok AS. Hospital readmissions among patients with decompensated cirrhosis. Am J Gastroenterol 2012;107:247. - PMC - PubMed

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